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Eur J Pharmacol 570:212221 Malavaud B, Tack I, Jonca F, Praddaude F, Moro F, Ader JL, Plouet J (1997) Activation of Flk-1/KDR mediates angiogenesis but not hypotension

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While there are no universally agreed-upon "optimal" ranges, practitioners and specialty lab testing companies may base these on the levels of micronutrients in the blood that are associated with the best health outcomes (not just the absence of disease) in clinical research studies